Journal Topics
- • General Medicine
- • Internal Medicine
- • Cardiology
- • Neurology
- • Oncology
- • Pediatrics
- • Surgery
- • Obstetrics and Gynecology
- • Orthopedics
- • Dermatology
- • Endocrinology
- • Nephrology
- • Gastroenterology
- • Pulmonology
- • Infectious Diseases
- • Epidemiology
- • Public Health
- • Clinical Pharmacology
- • Immunology and Allergy
- • Pathology
- • Radiology
- • Medical Genetics
- • Rheumatology
- • Hematology
- • Anesthesiology
- • Emergency Medicine
- • Critical Care Medicine
- • Precision Medicine
- • Personalized Healthcare
- • Regenerative Medicine
- • Telemedicine and Digital Health
- • Medical Education
- • Healthcare Management
- • Artificial Intelligence in Medicine and more.
Abstract
Appropriate Use of Antibiotics for the Treatment of Community Acquired Pneumonia in Children at Tertiary Hospital in Vietnam
Objective: To describe and analyse the use of appropriate antibiotics for the treatment of community-acquired pneumonia (CAP) in children aged 2 months to 5 years in a tertiary hospital in Vietnam.
Methods: A cross-sectional descriptive study was carried out based on retrospective data and information collected from 154 inpatient medical records for community-acquired pneumonia (CAP) at the Paediatric Department of Bach Mai Hospital, Hanoi, Vietnam in 2021.
Results: Clinical and laboratory information, antibiotic use was collected in order to describe and analyse appropriate use of antibiotics for community-acquired pneumonia in children aged 2 months to 5 years. There were 12 initial antibiotic regimens selected for the treatment of CAP. Of those, four regimens used a single antibiotic and eight regimens used a combination of antibiotics. The proportion of combination regimens increased with the severity of the disease, with 22.3%; 38.5% and 50% for mild pneumonia, severe pneumonia and very severe pneumonia, respectively. The most commonly used antibiotic groups in the initial regimen are penicillin/β-lactamase inhibitor (alone regimen) and penicillin/β-lactamase inhibitor in combination with macrolides (combination regimen). The rate of initial treatment regimens not following recommendations was up to 99.4%. There were 83/154 cases where patients were prescribed antibiotics with inappropriate dosages.
Conclusion: The rate of inappropriate use of antibiotics in the treatment of CAP in children in a tertiary hospital was still high. It is necessary to develop a system of assessment and monitoring of antibiotic use in order to reduce inappropriate use of antibiotics and drug resistance of bacteria.