Innovative Insights in Case Reports and Reviews

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  • • Cardiology and Cardiovascular Medicine
  • • Neurology and Neuropsychiatry
  • • Oncology and Cancer Research
  • • Pediatrics and Child Health
  • • Gastroenterology and Hepatology
  • • Endocrinology and Diabetes Care
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  • • Surgery and Surgical Innovations
  • • Orthopedics and Musculoskeletal Disorders
  • • Dermatology and Skin Care
  • • Dentistry and Oral Health

Abstract

Stimulation of the Wound Healing Process of an Electrocution-Associated Ulceration Using Amniotic Membrane: A Case Study
Alison Ingraldi, Daniel Davis, Darlene Lee and Aaron J. Tabor.

Electrical injuries can result in significant tissue damage\r\ndue to both thermal and electrical effects. The healing process for these\r\nwounds is complicated by factors such as vascular damage, tissue necrosis, and\r\nan increased risk of secondary infections. Approximately 3–5% of admissions to\r\nburn centers worldwide are due to electrocution injuries. Unlike thermal burns,\r\nelectrical burns can penetrate deeply into the tissue because of the electrical\r\ncurrent, leading to muscle necrosis and vascular injury, along with potential\r\ncomplications such as chronic ulcers. Healing from these injuries often\r\nprogresses slowly; wounds may stall and necessitate aggressive treatments,\r\nincluding debridement, skin grafting, and additional therapies like hyperbaric\r\noxygen treatment and biological skin substitutes. This clinical case study aims\r\nto assess the clinical efficacy of a commercial dehydrated amniotic membrane\r\n(dHAM) allograft in promoting wound healing in a chronic, non-healing\r\nneuropathic ulcer secondary to a high-voltage electrical injury in a\r\n50-year-old male patient, resulting in extensive burns on his right arm, chest,\r\nand left lower extremity that have remained open since the etiologic event. The\r\ncase report outlines the clinical interventions for wound management strategies\r\nusing a commercial allograft dehydrated amniotic membrane (dHAM) product that\r\ndemonstrated the stimulation of the wound healing cascade with a 44% reduction\r\nin wound size specifically for the patient’s neuropathic ankle ulcer.

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